The Sussex County Unified Sanitary Sewer District serves the following areas:
- Angola Neck
- Bay View Estates
- Bethany Beach
- Blackwater Village
- Blades
- Cedar Neck
- Chapel Branch Area
- Dagsboro-Frankford
- Dewey Beach
- Ellendale
- Fenwick Island
- Golf Village
- Henlopen Acres
- Herring Creek
- Holts Landing
- Indian River Acres
- Johnsons Corner
- Long Neck
- Miller Creek
- Millville
- Mulberry Knoll
- North Bethany
- Oak Orchard
- Ocean View
- Ocean Way Estates
- Pintail Pointe
- Sea Country Estates
- Slaughter Beach
- South Bethany
- South Ocean View
- Sussex Shores
- West Rehoboth
- Western Sussex (Bridgeville/Greenwood)
- Winding Creek Village
- Woodlands of Millsboro